The two most common systems in independent primary care, and they lead different specialties.
athenahealth
eClinicalWorks
User rating
3.8/5 · 911 reviews
3.3/5 · 396 reviews
Practice sizes served
2–5, 6–15, 16–50, 50+
1 (solo), 2–5, 6–15, 16–50, 50+
Smallest practice served
2–5
1 (solo)
System type
Cloud-Based, All-in-One, Small Practice
Cloud-Based, All-in-One
Specialties served
26 of 30
27 of 30
Published price
Quote only — not published
$449–$599 per provider / month
Share of identified providers
24.4% (n=9,098)
15.2% (n=5,677)
Where they stand in independent practice
Across the 37,310 providers whose EMR is identifiable in the federal registry, athenahealth accounts for 24.4% and eClinicalWorks for 15.2%.
athenahealth
24.4%
eClinicalWorks
15.2%
Where they meet, by specialty
Specialties in which at least one of the two is a registry top-three system. A dash means that vendor is not in the top three for that specialty — not that it is absent from the market.
Specialty
athenahealth
eClinicalWorks
n
Family Medicine
32.1%
15.3%
10,004
Orthopedics
31.1%
14.5%
1,220
Internal Medicine
30.8%
17.5%
3,659
General Surgery
20.4%
26.2%
1,904
Cardiology
25.5%
21%
1,360
Pediatrics
25.2%
16.5%
1,433
Obstetrics & Gynecology
23.1%
24.7%
2,175
Otolaryngology (ENT)
24.5%
—
368
Neurology
21.8%
24.2%
619
Endocrinology
23.2%
15.9%
220
Gastroenterology
21.6%
16.9%
486
Nephrology
21.3%
20.5%
239
Physical Therapy
20.3%
—
413
Podiatry
18.5%
—
303
Urology
17.6%
—
391
Pulmonology
17.3%
—
548
Emergency Medicine
15.1%
—
405
Allergy & Immunology
—
10.7%
75
Occupational Therapy
7.1%
—
85
Which one to shortlist
Choose athenahealth if…
Users rate it higher — 3.8/5 across 911 reviews, against 3.3/5.
Choose eClinicalWorks if…
Your practice is smaller than athenahealth sells to. eClinicalWorks lists 1 (solo) as its smallest tier, against 2–5.
You want a number before you talk to sales. eClinicalWorks publishes $449–$599 per provider / month; athenahealth quotes privately.
Get a real comparison for your practice
Everything above is what we can say about these two in general. What we cannot tell you from a page is what either costs at your provider count, in your specialty. Tell us and we will get you quotes from the vendors that actually fit — free, and we never charge practices.
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Other comparisons
Epic vs athenahealthOracle Health (Cerner) vs athenahealthathenahealth vs AdvancedMDTebra (Kareo) vs AdvancedMDPractice Fusion vs Tebra (Kareo)NextGen vs Modernizing MedicineModernizing Medicine vs CompulinkeClinicalWorks vs NextGenVeradigm (Allscripts) vs eClinicalWorks
Share figures are EMR Match Research analysis of the CMS NPPES Direct-endpoint data, July 2026 dissemination (n=37,310 identified providers) — the same source as our open data page, so the two can never disagree. This measures the EMR identified by the Direct-messaging endpoint a practice registered with the federal NPPES registry. Vendors that sell mainly to small independent practices are systematically under-represented, because small practices are the least likely to have registered an endpoint at all. Read it as a floor, not as installed base. Ratings and prices are as published by the review source and the vendor; sourcing on our methodology page.